TNFSF10 and type 1 diabetes mellitus: It has been shown that the repression of pro-apoptotic pathways (the Fas/FasL and TRAIL/TRAIL-R pathways) by microRNAs leads to unrestricted expansion of diabetogenic CD8+ T cells, suggesting microRNAs may mediate gene silencing in islet cell autoimmunity in T1D patients (153).