One example of the SNP of IL1RL1 that predisposes to both atopic and non-atopic asthma and is connected with eosinophilia, causing an increased level of serum IgE and airway hyperresponsiveness, is rs950880 for non-Islandic population (in Islandic population it is rs1420101) (60, 61). Here, IL1RL1 is linked to asthma.