CRP and Parkinson disease: Results have indicated significant increase of CRP levels in PD subjects when compared with control groups in serum (SMD = 1.115, 95% CI 0.619-1.61, <i>P</i> < 0.001), CSF (SMD = 1.127, 95% CI 0.133-2.120, <i>P</i> = 0.026) as well as whole blood (SMD = 1.071, 95% CI 0.715-1.426, <i>P</i> < 0.001).