Strong LD was observed between rs878567 and rs6295 of the 5-HT1A gene (D′= 1.0, r2 = 0.72), but haplotype-based analysis found that the 5-HT1A gene rs878567-rs6295 haplotype was not associated with MDD (p = 0.040, permuted p = 0.242). Here, HTR1A is linked to major depressive disorder.