OSBPL8 and diabetes mellitus: In Figure 5A, to demonstrate the proof of principle, we showed how circRNA has_circ_30156 could inhibit type 2 diabetes mellitus (T2DM) by sponging miR143 and preventing miR143 from binding to oxysterol-binding protein-related protein 8 (ORP8) 3′untranslated region (3′UTR).