GHSR and Anxiety: Also, intraperitoneal injection of sertraline during the CSDS procedure did not affect anxiety-like behavior (Figure 2D; Ghsr-/- mice CSDS vs. Sertraline + CSDS, P > 0.05) or despair-like behavior (Figure 2E; Ghsr-/- mice CSDS vs. Sertraline + CSDS, P > 0.05) of Ghsr-/- mice.