To identify an association between epidermal AMBRA1 expression overlying primary tumours (peritumoral AMBRA1) and DFS in patients with AJCC stage I melanoma, 76 patients within the NUTH cohort were stratified as either having maintained or decreased AMBRA1 expression by visual analysis of peritumoral AMBRA1 expression (Fig. 2). This evidence concerns the gene AMBRA1 and neoplasm.