Intraocular secretion of XFM is closely related to aqueous circulation; therefore, examination of aqueous humour and lens epithelial cell composition in patients with XFS may reveal important pathogenetic factors.19 In recent years, LOXL1 single nucleotide polymorphisms (SNPs) have been identified as a risk factor for XFS. The gene discussed is LOXL1; the disease is exfoliation syndrome.