The CD3+ and CD8+ TIL burden was greater in diagnostic tumor specimens from HGS OC patients who went on to experience ILNR when compared with their ENR counterparts (median CD3+ cell density 1.94% vs 1.13%, P = .001 and median CD8+ cell density 0.90% vs 0.45%, P = .009; Bonferroni-adjusted P = .003 and P = .019) (Figure 2, B). This evidence concerns the gene CD8A and neoplasm.