Moreover, using 64 paraffin-embedded tissues, we found that the rate of positive HMGA2 expression was significantly higher in NF1 MPNST samples (13/16) than in sporadic MPNST (16/41) and neurofibroma (0/7) samples (Fig. 1e and Table 1). Here, HMGA2 is linked to neurofibromatosis type 1.