IRF4 and Miyoshi myopathy: The most frequently mutated genes in MM patients are: KRAS (23%), NRAS (20%), FAM46C (11%), DIS3 (11%), and TP53 (8%); and less frequent, but recurrent mutated genes are: BRAF, TRAF3, PRDM1, CYLD, RB1, IRF4, EGR1, MAX, HIST1H1E, and ACTG1 [11,12].