ESR1 and breast carcinoma: Results obtained by Corsetto et al. also revealed that PUFAs (polyunsaturated fatty acids) induce cell apoptosis and cause a reduction of cell viability in two lines of human breast cancer cells characterized by a different expression of ER (estrogen receptor) and EGFR (epidermal growth factor receptor) receptors—MDA-MB-231 (ER-negative) and MCF-7 (ER-positive) [45].