PADI4 and rheumatoid arthritis: PAD4, the most prominent among PADs, plays a role in tumorigenesis by influencing the expression of p53 target genes and is strongly implicated in the pathogenesis of atherosclerosis by modulating of the function of chemokines, antibacterial neutrophil extracellular traps (NETs) formation and in the generation of new autoantigens in rheumatoid arthritis (RA) [5].