PARK7 and Parkinson disease: The HSP mortalin in the mitochondria of hematopoietic stem cells interacts with the antioxidant deglycase protein 1(DJ-1), which is implicated in Parkinson’s disease, and the mortalin/DJ-1 complex allows sustaining hematopoietic stem cell quiescence, abundance, and self-renewal capacity, because it protects the mitochondria of these cells from ROS accumulation and oxidative macromolecular damage (Figure 5) [304].