Furthermore, CYP2B6 and CYP3A4, the human homologues of Cyp2b10 and Cyp3a11 (another CYP induced in this study), are central in the metabolism (N-demethylation) of clobazam, an anti-seizure medication used in the treatment of epilepsy. The gene discussed is CYP3A4; the disease is epilepsy.