The genetic overlap between VKCFD1 and PXE-like syndrome, though a distinct phenotypic presentation, may be explained by the fact that mutations causing PXE-like syndrome seem to typically occur in exons 8, 10, and 12 of the GGCX gene, while no such mutations have been found so far in VKCFD1 [13]. The gene discussed is GGCX; the disease is body skin hyperlaxity due to vitamin K-dependent coagulation factor deficiency.