To investigate the role of bLf on iron homeostasis of mice infected by P. aeruginosa, lung homogenates of WT and CF mice, treated with saline or bLf, were analysed for the expression of the main iron-related proteins involved in cell and systemic iron homeostasis, namely Fpn, Ftn and TfR1, and total iron content in the BALF was also assessed. The gene discussed is TFRC; the disease is cystic fibrosis.