TGM2 and neoplasm: Adipose tissue can constitute a proinflammatory microenvironment in obese patients, leading to stromal activation which is associated with more aggressive tumor behavior and poor prognosis.25, 26, 27, 28, 29 Negative regulators of adipogenesis like BMP and activin membrane‐bound inhibitor (BAMBI) or transglutaminase 2 (TGM2) showed the lowest expression in Group 1 (Supporting Information Fig. S6).30, 31