The results suggested significant reduction of miR‐1281 expression with upregulated GIHCG (Figure 3d), further demonstrating that miR‐1281 was a target gene of GIHCG. Detection of miR‐1281 expression in GC showed a significantly low expression of miR‐1281 in GC (Figure 3e) and negative correlation with GIHCG expression in GC (Figure 3f). The gene discussed is GIHCG; the disease is gastric cancer.