HAND2 and endometrial cancer: For example, UCA1 has been reported as an oncogenic lncRNA in endometrial cancer, and silencing UCA1 inhibited endometrial cancer cell migration.15 lncRNA FER1L4 is down‐regulated in endometrial cancer and suppresses cancer cell proliferation by regulating PTEN expression.16 lncRNA HAND2‐AS1 inhibits invasion and metastasis in EECs through inactivation of neuromedin U.17 Nevertheless, the functions and clinical significance of lncRNAs in EEC remain unexplored.