CD8A and metastatic malignant neoplasm in the lymph nodes: Occurrence of axillary lymph node metastasis was significantly related with cell counts of CD8+/PD1− TILs, median cell counts being 27/HPF among cases with axillary lymph node metastasis, significantly higher than those among cases without axillary lymph node metastasis (11/HPF, Table 3).