Similar to cisplatin-treated Oasl1−/− mice, CD8+ T and NK cells (cytotoxic effector cells), as well as CD8α+ DCs (major cells cross-presenting tumor antigen to CD8+ T cells), which were present in a much higher proportion within CD45+ cells in the lungs of irradiated Oasl1−/− mice, and MDSCs (present in a lower number in the lungs of irradiated Oasl1−/− mice) might contribute to the more effective antitumor immune response in the irradiated Oasl1−/− mice. The gene discussed is PTPRC; the disease is neoplasm.