Anti-GAPDH autoantibodies were also marginally correlated with increased ESR (r = 0.323, P = 0.066) and serum IgM (r = 0.306, P = 0.078) in NPSLE patients (Table 3), similar to the result from the whole SLE patients. The gene discussed is GAPDH; the disease is systemic lupus erythematosus.