According to the previous reports, GAPDH was identified as a target antigen reacting with the serum from patients with autoimmune diseases, such as SLE, Behçet's disease (BD), dermatomyositis (DM), rheumatoid arthritis (RA), and Takayasu's arteritis (TA) [17, 18]. This evidence concerns the gene GAPDH and rheumatoid arthritis.