Based on the published literature, JNK and p38 are the most frequently activated MAPKs in response to NBP-induced cancer apoptosis, with effects having been reported in head and neck cancer [78], colorectal cancer [79], thyroid cancer [43], cervical cancer [80], and melanoma [81], among which colorectal cancer cell ERK was also activated. This evidence concerns the gene MAPK8 and colorectal cancer.