Western blot analysis of lung tissues in BLM-induced lung fibrosis mice showed an increased expression of extracellular matrix proteins, such as fibronectin, and phosphorylation of STAT3 (Tyr705) protein, a downstream mediator of IL-6 signaling, when compared with lung tissues of the control mice (Figure 5(a)). This evidence concerns the gene FN1 and pulmonary fibrosis.