The lung fibrosis-related cytokines IL-6 and IL-33 were significantly increased in the blood of mice with BLM-induced lung injury by day 14 compared with the control mice, indicating that IL-6 and IL-33 may associate with lung injury and muscle wasting in BLM-induced lung fibrosis mouse models (Figures 4(b) and 4(c)). This evidence concerns the gene IL33 and pulmonary fibrosis.