EGFR and non-small cell lung carcinoma: EGFR-TKIs have been found to be more effective in the treatment of patients with BM than chemo- and/or radiotherapy [3,4]; however, few studies have explored the clinical characteristics, treatment options, and prognoses of NSCLC patients with BM following surgical resection, in spite of the fact that more and more NSCLC patients are currently being diagnosed at the early stage of disease.