In the zebrafish ADPKD model, a translation blocking morpholino oligomer complementary to the ATG of pkd2 (MO pkd2) is injected into the embryos at the 1 cell stage, causing a large dilation of the glomeruli (cysts) two days later42 (Fig. 8b). The gene discussed is PKD2; the disease is autosomal dominant polycystic kidney disease.