Previous studies have identified associations between rs5186 in AGTR1 and diseases including coronary artery disease,46 systemic lupus erythematosus47 and cancer.48 Several smaller studies had also been undertaken to assess links between this gene and renal disease.25 49–54 We conducted this study to provide a clearer understanding of the effect of this SNP on CKD. This evidence concerns the gene AGTR1 and chronic kidney disease.