Pairwise comparisons (Dunn test with Bonferroni correction) showed (1) for AD versus CTL, increased C4 and eotaxin-1, decreased sCR1, C5, and CRP; (2) for MCI versus CTL, increased FH, C3, and MCP-1, decreased C5 and MIP-1b; (3) for AD versus MCI, increased eotaxin-1 and MIP-1b, decreased FI, C3, CRP, MCP-1 (Table 1; Fig. 1). The gene discussed is CRP; the disease is Alzheimer disease.