In patient group I, apoM concentrations were significantly lower in patients with active renal disease (glomerulonephritis, e.g., urinary casts, proteinuria, hematuria, or pyuria) and skin involvement (rash), compared to patients without these organ manifestations (p < 0.01 and p = 0.01, respectively, Fig. 3). The gene discussed is APOM; the disease is kidney disorder.