MKI67 and neoplasm: Thisproportion is lower than reported in other studies, which reported ranges from 20%to 30%.1,5,22,30 Our double-expressing cases showed a significantlyhigher Ki67 proliferation index, in keeping with the tumor biology, a findingreplicated in the same studies.1,5,22,30 Double-expressingDLBCL also occurs in slightly older individuals,2 which we also found in the current study, with a median ageof 61 years for patients with double-expressing DLBCL, compared with 49 years forpatients with non–double-expressing DLBCL (P = .0178).