CD274 and neoplasm: From these biodistribution studies, MDA-MB231 tumor, spleen, and lymph node tissues were prepared for H&E and PD-L1 IHC staining to confirm that the [89Zr]Zr-DFO-PD-L1 mAb uptakes in these tissues represent specific targeting to PD-L1 (Figure 5 A-C).