These IHC results correspond with the [89Zr]Zr-DFO-PD-L1 mAb uptakes observed in these tissues in which the spleen and lymph nodes exhibited the highest uptakes compared to the lower tumor uptakes indicating that [89Zr]Zr-DFO-PD-L1 mAb is able to distinguish PD-L1 expression levels in vivo. The gene discussed is CD274; the disease is neoplasm.