Paired box 8 (PAX8) could affect the development of the kidney, eye, thyroid gland, central nervous system, and organs derived from the Müllerian duct.28 PAX8 could influence the expression of thyroid‐specific genes as a transcription factor.29, 30 Nonaka et al demonstrated that the expression levels of PAX8 in PTC, follicular thyroid carcinoma, and poorly differentiated thyroid carcinoma were invariable. This evidence concerns the gene PAX8 and thyroid gland follicular carcinoma.