Paired box 8 (PAX8) could affect the development of the kidney, eye, thyroid gland, central nervous system, and organs derived from the Müllerian duct.28 PAX8 could influence the expression of thyroid‐specific genes as a transcription factor.29, 30 Nonaka et al demonstrated that the expression levels of PAX8 in PTC, follicular thyroid carcinoma, and poorly differentiated thyroid carcinoma were invariable. The gene discussed is PAX8; the disease is poorly differentiated thyroid gland carcinoma.