FOXO4 and Cowden syndrome 1: Previous research indicated that the somite development of rat begins from GD 9 and ends on GD 16, with the fastest stage at GD 11 when approximately 21‐33 somites (from lower thoracic to sacral) are developed.36, 37 We specifically observed dynamic changes in the expression of the SULT1C2A‐rno‐miR‐466c‐5p‐Foxo4 axis over GDs 8 to 15, especially from GDs 9 to 11, suggesting that the spatiotemporal changes in the expression of the SULT1C2A‐rno‐miR‐466c‐5p‐Foxo4 axis are important for somitogenesis in VAD‐induced CS.