NR2E3 and non-small cell lung carcinoma: Here, we have investigated the effects of subclinical concentrations of gemcitabine and HU in NSCLC and melanoma cell lines and TS cultures, and in normal skin fibroblasts to compare the effects of these RNR inhibitors on synergy with the CHK1i GDC‐0575 (Oo et al., 2018).