Transcripts increased by more than 16 fold change in SLE monocytes compared to both T and B cells included IL1RN, SERPING1, PLSCR1, EIF2AK2, JAK2, and CXCL10. LAMP3 was overexpressed in SLE T cells compared to SLE monocytes and B cells and APOBEC3B, STAP1, and SPIB were overexpressed in SLE B cells compared to SLE monocytes and T cells (Supplementary Data 30). The gene discussed is APOBEC3B; the disease is systemic lupus erythematosus.