Figure 5a, b demonstrates the significant differences in staining patterns between representative tumors: the reference wild-type BCL2 genotype did not display staining in tumor cells (infiltrating lymphocytes stained positively), while patients with a C at location 21 of BCL2 (Fig. 5c) displayed positive cytoplasmic staining in tumor cells, indicating the accumulation of BCL2. Here, BCL2 is linked to neoplasm.