In the present study, tyrosine serum levels were significantly positively correlated with the serum levels of NT-proBNP, IL-6, and 2-HB (r = 0.24, P = 0.007), the markers of HF severity, inflammation, and oxidative stress, respectively, which are known to be associated with increased muscle proteolysis and protein turnover46,47. The gene discussed is IL6; the disease is hydrops fetalis.