Hanin [17] found that miRNA-608 could interact with the validated cell division control protein 42 homolog and interleukin-6 targets in vitro and in vivo and that the consequences of these interactions can change cortisol levels and blood pressure.Yang found that esophageal squamous cell carcinoma patients with the GG genotype of miRNA608:rs4919510 had a 4.56-fold increased risk of high IL-6 expression compared with that in patients with the CC genotype [18]. The gene discussed is IL6; the disease is esophageal squamous cell carcinoma.