Plasma SOD activity was higher in T2DM groups when compared to control (control: 1.67 [1.39–1.93] vs. group A: 2, 95 [2.22–3.55], p <0.001; vs. group B: 2.18 [1.97–3.34], p<0.01 and vs. group C: 2.38 [1.97–3.74]; p <0.01). This evidence concerns the gene SOD1 and type 2 diabetes mellitus.