VEGFA and fetal growth restriction: The role of angiopoetin depends on the presence of proangiogenic factors, especially vascular endothelial growth factor (VEGF), whose level is modulated by its soluble receptor (sVEGFR known as sFlt-1) in placentas complicated by IUGR (Khalig et al. 1999; Nevo et al. 2008; Yinon et al. 2014).