In these four clusters, seven proteins were found in the two calcification-prone donors but not in the same clusters of the two calcification-resistant donors in OM (Figure 6C): CDC42 effector protein 4 (CDC42EP4), gamma-glutamyltransferase 5 (GGT5), heterogeneous nuclear ribonucleoprotein M (HNRNPM), monoamine oxidase A (MAOA), stromal interaction molecule 1 (STIM1), transglutaminase 2 (TGM2), and zinc fingers and homeoboxes 2 (ZHX2). The gene discussed is ZHX2; the disease is ocular melanoma.