CALR and cancer: For example, in acute myeloid leukemia (AML), indolent B-cell lymphoma, non-small cell lung cancer (NSCLC), ovarian cancer, glioblastoma, endometrial cancer or colon cancer, the increased expression of CRT correlates with a favorable clinical outcome, as well as (in some cases) with increased levels of biological markers related to an active anti-cancer immune response (Peng et al., 2010; Zappasodi et al., 2010; Garg et al., 2015b; Stoll et al., 2016; Fucikova et al., 2016a,b, 2018; Xu et al., 2018).