Validation with human pancreatic cancer cell lines (AsPC-1, PACN-1, SW-1990 for metastatic phenotype and Capan-2 for non-metastatic phenotype) and pancreatic cancer tissue sections showed that the expression level of REST was higher in advanced pancreatic cancer tissue samples and metastatic phenotype cell lines (Figures 3C–E, Table 1). Here, REST is linked to pancreatic neoplasm.