Despite the fact the Tu-2449 cells are immunogenic and express MHC on their cell surface (data not shown), unlike GL-261 cells which are reported to carry high tumor mutational burden (Genoud et al., OncoImmunology, https://doi.org/10.1080/2162402X.2018.1501137), their tumorigenic property is not induced by carcinogen and thus are most likely to have low tumor mutational burden which closely resembles human GBM. Here, HLA-C is linked to glioblastoma.