EIF4E and cutaneous melanoma: To further investigate a correlation between PHF14 gene expression and cellular protein synthesis, we analyzed expression of PHF14 gene and key regulator of protein synthesis such as ribosomal protein S6 (rpS6), eukaryotic initiation factor 4E (eIF4E), or eukaryotic initiation factor 4B (eIF4B) in the Cancer Genome Atlas (TCGA) dataset [52], TCGA-SKCM (skin cutaneous melanoma, n=470) and TCGA-COAD (colon adenocarcinoma, n = 461), using GEPIA platform [53].