DTWD2 and bipolar disorder: Furthermore, a subunit for GABA receptor 1B (GABBR1), DTW Domain Containing 2 (DTWD2), and DISC1-Binding Zinc-Finger Protein (ZNF365), have been associated with multiple often comorbid disorders, including addiction, bipolar disorder, and schizophrenia (Ayyappan et al., 2009; Fatemi et al., 2011; Pan et al., 2013; Augier et al., 2018).