That study showed that APS patients having high levels of CXCL4/CXCL4L1 in plasma were characterized more often by IgG aCL, double antibody or triple antibody positivity, and presented more than 3 thrombotic events, thus underlying the relevance of the increased expression of these molecules in the occurrence of thrombosis. The gene discussed is PF4; the disease is autoimmune polyendocrinopathy.