The GRM3 gene was found associated to schizophrenia in large GWAS analysis (Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014) and it encodes for the mGluR3 receptor, with a prominent role in the glutamate signaling in the brain (Cartmell and Schoepp, 2000). Here, GRM3 is linked to schizophrenia.