FZD2 and neuroblastoma: Furthermore, our study did not align simply with reports showing that individual Wnt pathway components were associated with chemoresistance (FZD1; Flahaut et al., 2009), tumorigenic stem-like cells in human and mouse neuroblastoma (FZD6; Cantilena et al., 2011), and increased NB proliferation dependent on FZD2 (Zins et al., 2016).